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Multiplex Automated Genome Engineering (MAGE)

By: Risa Aria Schnebly | Published: Dec 10, 2020

Multiplex Automated Genome Engineering, or MAGE, is a genome editing technique that enables scientists to quickly edit an organism’s DNA to produce…

TechnologyGenetic EngineeringGenetic engineering industryGenetic epidemiologyGene libraries

Role of Sonic Hedgehog (Shh) in Alcohol-Induced Craniofacial Abnormalities

By: Erica O'Neil | Published: Oct 20, 2010

Prenatal exposure to alcohol (ethanol) results in a continuum of physical and neurological developmental abnormalities that vary depending on the…

fetal alcohol syndromeCongenital DisordersFetus

"Contributions to the Development of the Embryo. On the Artificial Production of One of the First Two Blastomeres, and the Later Development (Postgeneration) of the Missing Half of the Body" (1888), by Wilhelm Roux

By: Megan Kearl | Published: Jul 20, 2009

Wilhelm Roux was an influential figure in the early history of experimental embryology. Although he originally studied medicine, he was invited to be…

LiteratureRoux, Wilhelm, 1850-1924ExperimentsFrogsOva

The Genetic Control and Cytoplasmic Expression of 'Inducibility' in the synthesis of B-galactosidase" (1959), by Arthur B. Pardee, Francois Jacob, and Jacques Monod

By: Abhinav Mishra | Published: May 28, 2015

Between 1957 and 1959, Arthur Pardee, Francois Jacob, and Jacques Monod conducted a set of experiments at the Pasteur Institute in Paris, France,…

Genetic transformationGenetic recombinationEnzyme KineticsMessenger RNANobel Prize winners

Lynn Petra Alexander Sagan Margulis (1938-2011)

By: Dorothy Regan Haskett | Published: Mar 23, 2014

Lynn Petra Alexander Sagan Margulis was an American biologist, whose work in the mid-twentieth century focused on cells living together in a mutually…

Eukaryotic cellsMitosissymbiosisMitochondriaMicroorganisms--Evolution

Somites: Formation and Role in Developing the Body Plan

By: Corinne DeRuiter | Published: Oct 20, 2010

Somites are blocks of mesoderm that are located on either side of the neural tube in the developing vertebrate embryo. Somites are precursor…

Somatic cellsSomites

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene

By: Kristina Winikates | Published: Jan 01, 2012

The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene was identified in 1989 by geneticist Lap-Chee Tsui and his research team as the…

Cystic FibrosisReproductionCongenital DisordersHuman Development

Golgi Staining Technique

By: Sarah Taddeo, Erica O'Neil | Published: Mar 06, 2017

The Golgi staining technique, also called the black reaction after the stain's color, was developed in the 1870s and 1880s in Italy to make brain…

TechnologyGolgi, Camillo, 1843-1926Stains and staining (Microscopy)NeuronsMicroscope slides

"The Development of the Turtle Carapace" (1989), by Ann Campbell Burke

By: Guido Caniglia | Published: Oct 20, 2011

Ann Campbell Burke examines the development and evolution of vertebrates, in particular, turtles. Her Harvard University experiments, described in…

LiteratureExperimentsPublicationsTurtlesEvolution

"The Chemical Basis of Morphogenesis" (1952), by Alan M. Turing

By: Julia Damerow | Published: Jun 25, 2010

In 1952 the article "The Chemical Basis of Morphogenesis" by the British mathematician and logician Alan M. Turing was published in Philosophical…

LiteratureTuring, Alan, 1912-1954MorphogenesisPublicationsModels