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Camillo Golgi's Black Reaction for Staining Neurons

By: Isra Mishqat | Published: May 26, 2017

In 1873 Italy, Camillo Golgi created the black reaction technique, which enabled scientists to stain and view the structure of neurons, the…

TechnologyNeuronsAxonsDendritesSilver Nitrate

An Atlas of Fertilization and Karyokinesis of the Ovum (1895), by Edmund Beecher Wilson

By: Kevin M. Gleason | Published: Apr 20, 2017

Edmund Beecher Wilson in the US published An Atlas of Fertilization and Karyokinesis of the Ovum (hereafter called An Atlas) in 1895. The book…

LiteratureKaryokinesisFertilization (Biology)ConceptionDevelopmental Biology

"Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts" (1997), by Angelika E. Schnieke, et al.

By: Zane Bartlett | Published: Aug 19, 2014

In the 1990s, researchers working at the Roslin Institute in Edinburgh, Scotland, performed cloning experiments in collaboration with PPL…

CloningChristmas FactorBlood coagulation factor IXRoslin InstituteWilmut, Ian

“Transfer of a Human Zygote” (1973), by David De Kretzer, Peter Dennis, Bryan Hudson, John Leeton, Alexander Lopata, Ken Outch, James Talbot, and Carl Wood

By: Whitney Alexandra Tuoti | Published: Mar 25, 2021

On 29 September 1973, researchers David De Kretzer, Peter Dennis, Bryan Hudson, John Leeton, Alexander Lopata, Ken Outch, James Talbot, and Carl Wood…

LiteratureEmbryologyEmbryogenesisZygotesEmbryo Transfer

The Germ-Plasm: a Theory of Heredity (1893), by August Weismann

By: Yawen Zou | Published: Jan 26, 2015

Friedrich Leopold August Weismann published Das Keimplasma: eine Theorie der Vererbung (The Germ-Plasm: a Theory of Heredity, hereafter The Germ-…

LiteratureWeismann, August, 1834-1914. Keimplasma. EnglishGerm CellsHeredityInheritance of acquired characters

The Neuron Doctrine (1860-1895)

By: Isra Mishqat | Published: Jun 15, 2017

The neuron doctrine is a concept formed during the turn of the twentieth century that describes the properties of neurons, the specialized cells that…

NeuronsAxonsDendritesNervous SystemSynapses

Experimental Studies on Germinal Localization (1904), by Edmund B. Wilson

By: James Lowe | Published: Dec 22, 2014

At the turn of the twentieth century, Edmund B. Wilson performed experiments to show where germinal matter was located in molluscs. At Columbia…

Wilson, Edmund B. (Edmund Beecher), 1856-1939EmbryosEmbryologyDevelopmental BiologyLarvae

The Discovery of p53 Protein

By: Lijing Jiang | Published: Jan 21, 2011

The p53 protein acts as a pivotal suppressor of inappropriate cell proliferation. By initiating suppressive effects through induction of apoptosis,…

Tumor Suppressor Protein p53ExperimentsCancerCell Death

Ericsson Method of Sperm Separation

By: Alysse Blight | Published: Sep 20, 2019

In 1973, Ronald Ericsson developed the Ericsson method, which is a technique used to separate human male sperm cells by their genetic material.…

TechnologySex ChromosomesGonosomesSpermSpermatozoa

Hedgehog Signaling Pathway

By: Dorothy R. Haskett | Published: Jul 30, 2015

The hedgehog signaling pathway is a mechanism that directs the development of embryonic cells in animals, from invertebrates to vertebrates. The…

EmbryologyEmbryosWieschaus, Eric F.Cellular signal transductionDrosophila melanogaster