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Alejandro Sánchez Alvarado's laboratory group has employed molecular tools to investigate old questions about regeneration and as a result have…
RegenerationExperimentsResearch in chemical induction seeks to identify the compound or compounds responsible for differentiation in a developing embryo. Soren Lovtrup…
Cell differentiationEmbryosDevelopmental BiologyNotochordWaddington, C. H. (Conrad Hal), 1905-1975The Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes,…
Y ChromosomeTestisEmbryosChromosomesSex ChromosomesIn 1961, Mary Lyon, a researcher who studied genetics, published “Gene Action in the X-chromosome of the Mouse (Mus Musculus L.),” hereafter “Gene…
Sex ChromosomesChromosomes, Human, XX chromosomeGenes, X-linkedX Chromosome InactivationAlec John Jeffreys created a process called DNA fingerprinting in the UK during the twentieth century. For DNA fingerprinting, technicians identify a…
DNA fingerprintingForensic sciencesForensic AnthropologyMicrosatellites (Genetics)Exons (Genetics)The hedgehog signaling pathway is a mechanism that regulates cell growth and differentiation during embryonic development, called embryogenesis, in…
Drosophila melanogasterCyclopiaGenetic regulationZebra danioGenesIn 1980 Janet Rossant and William I. Frels published their paper, "Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between…
ChimeraExperimentsMiceAnencephaly is an open neural tube defect, meaning that part of the neural tube does not properly close or that it has reopened during early…
fetal developmentFetus--AbnormalitiesBirth DefectsEmbryologyPregnancyIn 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsIn June 2015, the Ethics Committee of the American Society for Reproductive Medicine, or ASRM, published “Use of reproductive technology for sex…
LiteratureSex PreselectionFertilization in VitroReproductive technologyHuman reproductive technology