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Calvin Bridges’ Experiments on Nondisjunction as Evidence for the Chromosome Theory of Heredity (1913-1916)
By: Kevin Gleason
| Published: May 18, 2017
From 1913 to 1916, Calvin Bridges performed experiments that indicated genes are found on chromosomes. His experiments were a part of his doctoral…
DrosophilaHeredityInheritance of acquired charactersColumbia University--Graduate studentsMutation
"Gene Regulation for Higher Cells: A Theory" (1969), by Roy J. Britten and Eric H. Davidson
By: Justin Wolter
| Published: Sep 10, 2013
In 1969, Roy J. Britten and Eric H. Davidson published Gene Regulation for Higher Cells: A Theory, in Science. A Theory proposes a minimal model…
LiteratureGenetic regulationCell differentiationEvolutionGenes
Embryonic Sex Differentiation and Sex Hormones (1947), by Carl R. Moore
By: Mary Drago
| Published: May 03, 2014
In 1947, Carl Richard Moore, a researcher at the University of Chicago, in Chicago, Illinois, wrote Embryonic Sex Differentiation and Sex Hormones,…
LiteratureEndocrinologyHormones, SexGonadal Steroid HormonesFreemartinism
"The Origin and Behavior of Mutable Loci in Maize" (1950), by Barbara McClintock
By: Federica Turriziani-Colonna
| Published: Oct 24, 2014
The Origin and Behavior of Mutable Loci in Maize, by Barbara McClintock, was published in 1950 in the Proceedings of the National Academy of Sciences…
LiteratureMcClintock, Barbara, 1902-1992ChromosomesTransposonsCorn
“A Proposed Structure for the Nucleic Acids” (1953) by Linus Pauling and Robert Brainard Corey
By: Victoria Hernandez
| Published: Aug 26, 2019
In February 1953, Linus Pauling and Robert Brainard Corey, two scientists working at the California Institute of Technology in Pasadena, California,…
LiteratureDNAGeneticsX-ray crystallography--TechniqueCrystallography, X-Ray
"Evolution and
Tinkering" (1977), by Francois Jacob
By: Valerie Racine
| Published: Oct 24, 2014
In his essay Evolution and Tinkering, published in Science in 1977, Francois Jacob argued that a common analogy between the process of evolution by…
LiteratureInstitut Pasteur (Paris, France)OperonsGenetic regulationNobel Prizes
“An Extended Family with a Dominantly Inherited Speech Disorder” (1990), by Jane A. Hurst et al.
By: Kat Fowler
| Published: Mar 23, 2017
In 1990, researcher Jane Hurst and her colleagues published “An Extended Family With a Dominantly Inherited Speech Disorder,” in which they proposed…
LiteratureGeneticsGenetic and developmental diseases and disordersapraxiaLinguistics
"RNA-Guided Human Genome Engineering via Cas 9" (2013), by Prashant Mali, Luhan Yang, Kevin M. Esvelt, John Aach, Marc Guell, James E. DiCarlo, Julie E. Norville, and George M. Church
By: Meilin Zhu
| Published: Dec 27, 2017
In 2013, George Church and his colleagues at Harvard University in Cambridge, Massachusetts published RNA-Guided Human Genome Engineering via Cas 9,…
Literaturegene editingTranscription Activator-Like Effector NucleasesscFV green fluorescent protein, recombinantClustered Regularly Interspaced Short Palindromic Repeats
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
“Use of reproductive technology for sex selection for nonmedical reasons” (2015), by the Ethics Committee of the American Society for Reproductive Medicine
By: Alysse Blight
| Published: May 27, 2019
In June 2015, the Ethics Committee of the American Society for Reproductive Medicine, or ASRM, published “Use of reproductive technology for sex…
LiteratureSex PreselectionFertilization in VitroReproductive technologyHuman reproductive technology