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"Presence of Fetal DNA in Maternal Plasma and Serum" (1997), by Dennis Lo, et al.
By: Cassidy Possehl
| Published: Mar 07, 2017
In the late 1990s researchers Yuk Ming Dennis Lo and his colleagues isolated fetal DNA extracted from pregnant woman’s blood. The technique enabled…
AmniocentesisChorionic Villus SamplingFetusObstetricsDNA
Oswald Theodore Avery (1877-1955)
By: Samantha Hauserman
| Published: Dec 12, 2013
Oswald Theodore Avery studied strains of pneumococcus of the genus Streptococcus in the US in the first half of the twentieth century. This bacterium…
Bacterial TransformationDNAHeredityPathologyImmunology
HeLa Cell Line
By: Rohini Nott
| Published: Sep 18, 2020
The HeLa cell line was the first immortal human cell line that George Otto Gey, Margaret Gey, and Mary Kucibek first isolated from Henrietta Lacks…
HeLa CellsContinuous cell linesResearch EthicsInformed consent (Medical law)Cervix uteri--Cancer
Embryonic Sex Differentiation and Sex Hormones (1947), by Carl R. Moore
By: Mary Drago
| Published: May 03, 2014
In 1947, Carl Richard Moore, a researcher at the University of Chicago, in Chicago, Illinois, wrote Embryonic Sex Differentiation and Sex Hormones,…
LiteratureEndocrinologyHormones, SexGonadal Steroid HormonesFreemartinism
Shoukhrat Mitalipov and Masahito Tachibana’s Mitochondrial Gene Replacement in Primate Offspring and Embryonic Stem Cells (2009)
By: Giselle Lee
| Published: Jan 10, 2018
Shoukhrat Mitalipov, Masahito Tachibana, and their team of researchers replaced the mitochondrial genes of primate embryonic stem cells via spindle…
monkeysrhesus macaqueSendai virusEmbryonic Stem CellsMitochondrial Diseases
Jennifer Doudna and Emmanuelle Charpentier’s Experiment About the CRISPR/cas 9 System’s Role in Adaptive Bacterial Immunity (2012)
By: Meilin Zhu
| Published: Oct 19, 2017
In 2012, Jennifer Doudna, Emmanuelle Charpentier from the University of California, Berkeley, in Berkeley, California, and Umeå University in Umeå,…
gene editingStreptococcus pyogenesTranscription Activator-Like Effector NucleasesscFV green fluorescent protein, recombinantClustered Regularly Interspaced Short Palindromic Repeats
Gene Transfer Strategy Used to Treat Tay - Sachs Disease (2005), by Sabata Martino’s Research Group
By: Tiffany Nardi
| Published: Feb 21, 2017
In the early 2000s, Sabata Martino and a team of researchers in Italy and Germany showed that they could reduce the symptoms of Tay-Sachs in…
Tay-Sachs DiseaseVirus-vector relationshipsGloboid Cell LeukodystrophyGangliosidesGene Therapy
"β-Catenin Defines Head Versus Tail Identity During Planarian Regeneration and Homeostasis" (2007), by Kyle A. Gurley, Jochen C. Rink, and Alejandro Sánchez Alvarado
By: Mary E. Sunderland
| Published: Mar 15, 2010
Alejandro Sánchez Alvarado's laboratory group has employed molecular tools to investigate old questions about regeneration and as a result have…
RegenerationExperiments
"Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between Mus musculus and Mus caroli" (1980), by Janet Rossant and William I. Frels
By: Nicole Newkirk
| Published: Oct 30, 2007
In 1980 Janet Rossant and William I. Frels published their paper, "Interspecific Chimeras in Mammals: Successful Production of Live Chimeras Between…
ChimeraExperimentsMice
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems