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"Male Development of Chromosomally Female Mice Transgenic for Sry gene" (1991), by Peter Koopman, et al.
By: Troy Cox
| Published: Jan 28, 2014
Early 1990s research conducted by Peter Koopman, John Gubbay, Nigel Vivian, Peter Goodfellow, and Robin Lovell-Badge, showed that chromosomally…
Y ChromosomeTestisEmbryosChromosomesSex Chromosomes
The Hershey-Chase Experiments (1952), by Alfred Hershey and Martha Chase
By: Victoria Hernandez
| Published: Jun 23, 2019
In 1951 and 1952, Alfred Hershey and Martha Chase conducted a series of experiments at the Carnegie Institute of Washington in Cold Spring Harbor,…
BacteriophagesDNACold Spring Harbor LaboratoryProtein PrecursorsAmino Acid Sequence
"Development, Plasticity and Evolution of Butterfly Eyespot Patterns" (1996), by Paul M. Brakefield et al.
By: Yawen Zou
| Published: Sep 10, 2013
Paul M. Brakefield and his research team in Leiden, the Netherlands, examined the development, plasticity, and evolution of butterfly eyespot…
ButterfliesDevelopmental BiologyPhenotypic plasticityGenotype-environment interactionEvolutionary developmental biology
"The linear arrangement of six sex-linked factors in drosophila, as shown by their mode of association” (1913), by Alfred Henry Sturtevant
By: Kevin Gleason
| Published: May 22, 2017
In 1913, Alfred Henry Sturtevant published the results of experiments in which he showed how genes are arranged along a chromosome. Sturtevant…
DrosophilaHeredityInheritance of acquired charactersColumbia University--Graduate studentsMutation
A Series of YouTube Videos Detailing the “CRISPR Babies” Experiment (2018), by He Jiankui
By: Risa Aria Schnebly, Brianna Ellis
| Published: Jul 31, 2021
In 2018, He Jiankui uploaded a series of videos to a YouTube channel titled “The He Lab” that detailed one of the first instances of a successful…
Literaturegene editingGenome EditingCRISPR (Genetics)CRISPR-associated protein 9
"Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts" (1997), by Angelika E. Schnieke, et al.
By: Zane Bartlett
| Published: Aug 19, 2014
In the 1990s, researchers working at the Roslin Institute in Edinburgh, Scotland, performed cloning experiments in collaboration with PPL…
CloningChristmas FactorBlood coagulation factor IXRoslin InstituteWilmut, Ian
The First Successful Cloning of a Gaur (2000), by Advanced Cell Technology
By: Caroline Appleton
| Published: Jul 26, 2013
Advanced Cell Technology (ACT), a stem cell biotechnology company in Worcester, Massachusetts, showed the potential for cloning to contribute to…
Cell nuclei--TransplantationCloningGaurAdvanced Cell Technology (Firm)Embryos
Using Digital PCR to Detect Fetal Chromosomal Aneuploidy in Maternal Blood (2007)
By: Meilin Zhu
| Published: Nov 08, 2017
In 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidy
Calvin Bridges’ Experiments on Nondisjunction as Evidence for the Chromosome Theory of Heredity (1913-1916)
By: Kevin Gleason
| Published: May 18, 2017
From 1913 to 1916, Calvin Bridges performed experiments that indicated genes are found on chromosomes. His experiments were a part of his doctoral…
DrosophilaHeredityInheritance of acquired charactersColumbia University--Graduate studentsMutation
"The Developmental Capacity of Nuclei Taken from Intestinal Epithelium Cells of Feeding Tadpoles" (1962), by John B. Gurdon
By: Giselle Lee
| Published: Mar 16, 2017
In 1962 researcher John Bertrand Gurdon at the University of Oxford in Oxford, England, conducted a series of experiments on the developmental…
Cell nuclei--TransplantationGenetic EngineeringNuclear TransplantationUniversity College (University of Oxford)Xenopus laevis