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"Gene Regulation for Higher Cells: A Theory" (1969), by Roy J. Britten and Eric H. Davidson
By: Justin Wolter
| Published: Sep 10, 2013
In 1969, Roy J. Britten and Eric H. Davidson published Gene Regulation for Higher Cells: A Theory, in Science. A Theory proposes a minimal model…
LiteratureGenetic regulationCell differentiationEvolutionGenes
Francis Harry Compton Crick (1916-2004)
By: Amanda Andrei
| Published: Nov 01, 2013
Francis Harry Compton Crick, who co-discovered the structure of deoxyribonucleic acid (DNA) in 1953 in Cambridge, England, also developed The Central…
DNAChromosomesNucleotide sequenceNucleic AcidsMolecular Biology
“A Proposed Structure for the Nucleic Acids” (1953) by Linus Pauling and Robert Brainard Corey
By: Victoria Hernandez
| Published: Aug 26, 2019
In February 1953, Linus Pauling and Robert Brainard Corey, two scientists working at the California Institute of Technology in Pasadena, California,…
LiteratureDNAGeneticsX-ray crystallography--TechniqueCrystallography, X-Ray
Sex-determining Region Y in Mammals
By: Troy Cox
| Published: Dec 31, 2013
The Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes,…
Y ChromosomeTestisEmbryosChromosomesSex Chromosomes
Alec John Jeffreys (1950–)
By: Corey Harbison
| Published: Jun 15, 2017
Alec John Jeffreys created a process called DNA fingerprinting in the UK during the twentieth century. For DNA fingerprinting, technicians identify a…
DNA fingerprintingForensic sciencesForensic AnthropologyMicrosatellites (Genetics)Exons (Genetics)
"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
Interspecies SCNT-derived Humanesque Blastocysts
By: Sarah Taddeo, Jason S. Robert, Nicole Diehnelt
| Published: Jun 23, 2017
Since the 1950s, scientists have developed interspecies blastocysts in laboratory settings, but not until the 1990s did proposals emerge to engineer…
BlastocystDiseasesbioethicsTadpoleCell nuclei--Transplantation
William Thomas Astbury (1898–1961)
By: Victoria Hernandez
| Published: Jun 03, 2019
William Thomas Astbury studied the structures of fibrous materials, including fabrics, proteins, and deoxyribonucleic acid, or DNA, in England during…
DNAX-Ray CrystallographyX-ray crystallography--TechniqueNucleic AcidsDNA-protein interactions
The Meselson-Stahl Experiment (1957–1958), by Matthew Meselson and Franklin Stahl
By: Victoria Hernandez
| Published: Apr 18, 2017
In an experiment later named for them, Matthew Stanley Meselson and Franklin William Stahl in the US demonstrated during the 1950s the semi-…
DNA ReplicationMeselson, MatthewStahl, Franklin W.DNA--SynthesisDNA
“A Sex Chromosome Anomaly in a Case of Gonadal Dysgenesis (Turner’s Syndrome)” (1959), by Charles Edmund Ford, K. W Jones, Paul E. Polani, J. C De Almeida, and J. H Briggs
By: Megha Pillai
| Published: Aug 06, 2024
In 1959, Charles Edmund Ford and colleagues published “A Sex Chromosome Anomaly in a Case of Gonadal Dysgenesis (Turner’s Syndrome),” hereafter “A…
Turner SyndromeGonadal DysgenesisGonadal Dysgenesis, XOGonadal Dysgenesis, 45, XAbnormalities, Sex Chromosome