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Victor Ambros is a professor of molecular medicine at the University of Massachusetts Medical School, and he discovered the first microRNA (miRNA) in…
PeopleRNAGenesEmbryosCaenorhabditis elegansThe source-sink model, first proposed by biologist Francis Crick in 1970, is a theoretical system for how morphogens distribute themselves across…
Crick, Francis, 1916-2004Nobel Prize winnersEmbryosMorphogenesisGenes'On the Permanent Life of Tissues outside of the Organism' reports Alexis Carrel's 1912 experiments on the maintenance of tissue in culture media. At…
Tissue cultureStem CellsStem cells--ResearchEmbryologyGerm CellsChristiane Nusslein-Volhard studied how genes control embryonic development in flies and in fish in Europe during the twentieth and twenty-first…
DrosophilaEmbryologyGenesMorphogenesisRNA polymerasesThe Spemann-Mangold organizer, also known as the Spemann organizer, is a cluster of cells in the developing embryo of an amphibian that induces…
EmbryosAmphibiansSpemann, Hans, 1869-1941EmbryologyGastrulationTwo main elements characterize the skeletal morphology of turtles: the carapace and the plastron. For a turtle, the carapacial ridge begins in the…
TurtlesMorphology (Animals)EmbryosGerm CellsEmbryologyThe epigenetic landscape is a concept representing embryonic development. It was proposed by Conrad Hal Waddington to illustrate the various…
Waddington, C. H. (Conrad Hal), 1905-1975EpigeneticsCell differentiationEmbryologyDevelopmental Biology"In vitro Experiments on the Effects of Mouse Sarcomas 180 and 37 on the Spinal and Sympathetic Ganglia of the Chick Embryo" were experiments…
Levi-Montalcini, RitaChickens--EmbryosHamburger, Viktor, 1900-2001Developmental BiologyEmbryologyEpidermal growth factor is a signaling molecule that stimulates the growth of epidermal tissues during development and throughout life. Stanley Cohen…
Levi-Montalcini, RitaHamburger, Viktor, 1900-2001EmbryologyEmbryosDevelopmental BiologyConrad Hal Waddington's "Experiments on Embryonic Induction III," published in 1934 in the Journal of Experimental Biology, describes the discovery…
Waddington, C. H. (Conrad Hal), 1905-1975EmbryosCell differentiationEmbryologyChickens--Embryos