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"CRISPR /Cas9-mediated Gene Editing in Human Tripronuclear Zygotes" (2015), by Junjiu Huang et al.
By: Meilin Zhu
| Published: Nov 08, 2017
In 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas Systems
Using Digital PCR to Detect Fetal Chromosomal Aneuploidy in Maternal Blood (2007)
By: Meilin Zhu
| Published: Nov 08, 2017
In 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidy
Jennifer Doudna and Emmanuelle Charpentier’s Experiment About the CRISPR/cas 9 System’s Role in Adaptive Bacterial Immunity (2012)
By: Meilin Zhu
| Published: Oct 19, 2017
In 2012, Jennifer Doudna, Emmanuelle Charpentier from the University of California, Berkeley, in Berkeley, California, and Umeå University in Umeå,…
gene editingStreptococcus pyogenesTranscription Activator-Like Effector NucleasesscFV green fluorescent protein, recombinantClustered Regularly Interspaced Short Palindromic Repeats
The China-US Study on the Prevention of Neural Tube Defects using Folic Acid (1999)
By: Dorothy Regan Haskett, Lauren Lynch
| Published: Oct 11, 2017
From 1993 to 1995 researchers led by Robert J. Berry from the US Centers for Disease Control headquartered in Atlanta, Georgia, and Zhu Li from…
Center for Disease ControlFolic AcidFolic Acid DeficiencyFolic acid in human nutritionNeural tube--Abnormalities
David H. Hubel and Torsten N. Wiesel’s Research on Optical Development in Kittens
By: Dina A. Lienhard
| Published: Oct 11, 2017
During 1964, David Hubel and Torsten Wiesel studied the short and long term effects of depriving kittens of vision in one eye. In their experiments,…
Harvard Medical SchoolNobel Prize winnersKittensCatsVision disorders
HIP Randomized Breast Cancer Screening Trial (1963–1982)
By: Dina A. Lienhard
| Published: Aug 08, 2017
From 1963 to 1982, researchers in New York City, New York, carried out a randomized trial of mammography screening. Mammography is the use of X-ray…
ExperimentsHIPMammographyBreastcarcinoma
Alec Jeffreys’s Experiments to Identify Individuals by Their Beta-globin Genes (1977-1979)
By: Corey Harbison
| Published: Jul 20, 2017
In a series of experiments in the late 1970s, Alec J. Jeffreys in the UK and Richard A. Flavell in the Netherlands developed a technique to detect…
DNA fingerprintingForensic sciencesGlobin genesNucleic acid hybridizationIn Situ Hybridization
Stanley Alan Plotkin's Development of a Rubella Vaccine (1969)
By: Christian H. Ross
| Published: Jun 28, 2017
In the US during the late 1960s, Stanley Alan Plotkin, John D. Farquhar, Michael Katz, and Fritz Buser isolated a strain of the infectious disease…
RubellaRubella--VaccinationRubella in pregnancyRubella vaccinesMMR Vaccine
Hox Genes and the Evolution of Vertebrate Axial Morphology Experiment (1995)
By: Joe Brinkman
| Published: Jun 23, 2017
In 1995, researchers Ann Burke, Craig Nelson, Bruce Morgan, and Cliff Tabin in the US studied the genes that regulate the construction of vertebra in…
Homeobox genesMorphology (Animals)Genes, HomeoboxGrowth and DevelopmentExperiments
"Control of Corneal Differentiation by Extracellular Materials" (1974), by Stephen Meier and Elizabeth D. Hay
By: Kevin Gleason
| Published: Jun 19, 2017
In 1974, Elizabeth Dexter Hay and Stephen Meier in the US conducted an experiment that demonstrated that the extracellular matrix, the mesh-like…
Extracellular matrixCollagenCorneaEpitheliumEmbryos