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Robert Geoffrey Edwards's Study of Fertilization of Human Oocytes Matured in vitro, 1965 to 1969
By: Lijing Jiang
| Published: Mar 10, 2011
Robert Geoffrey Edwards, a British developmental biologist at University of Cambridge, began exploring human in vitro fertilization (IVF) as a way to…
Fertilization in VitroExperimentsReproductionFertilizationOocytes
"Embryonic Stem Cell Lines Derived from Human Blastocytes" (1998), by James Thomson
By: Ke Wu
| Published: Feb 01, 2011
After becoming chief pathologist at the University of Wisconsin-Madison Wisconsin Regional Primate Center in 1995, James A. Thomson began his…
Stem CellsExperimentsPublicationsHuman Development
"Embryonic Stem Cell Lines Derived from Human Blastocytes" (1998), by James Thomson
By: Ke Wu
| Published: Feb 01, 2011
After becoming chief pathologist at the University of Wisconsin-Madison Wisconsin Regional Primate Center in 1995, James A. Thomson began his…
Stem CellsExperimentsPublicationsHuman Development
Nicole Le Douarin and Charles Ordahl's Experiments on the Developmental Lineages of Somites
By: Corinne DeRuiter
| Published: Jan 31, 2011
Through various studies developmental biologists have been able to determine that the muscles of the back, ribs, and limbs derive from somites.…
SomitesExperimentsSomatic cellsVertebrates
The Discovery of p53 Protein
By: Lijing Jiang
| Published: Jan 21, 2011
The p53 protein acts as a pivotal suppressor of inappropriate cell proliferation. By initiating suppressive effects through induction of apoptosis,…
Tumor Suppressor Protein p53ExperimentsCancerCell Death
"The Effects of Wing Bud Extirpation on the Development of the Central Nervous System in Chick Embryos" (1934), by Viktor Hamburger
By: Lijing Jiang
| Published: Nov 22, 2010
German embryologist Viktor Hamburger came to the US in 1932 with a fellowship provided by the Rockefeller Foundation. Hamburger started his research…
LiteraturePublicationsExperimentsNervous SystemChicks
"Generation of Induced Pluripotent Stem Cells without Myc from Mouse and Human Fibroblasts" (2007), by Masato Nakagawa et al.
By: Samuel Philbrick
| Published: Nov 20, 2010
In November 2007, Masato Nakagawa, along with a number of other researchers including Kazutoshi Takahashi, Keisuke Okita, and Shinya Yamanaka,…
LiteratureStem CellsPublicationsExperimentsMice
Viktor Hamburger's Study of Central-Peripheral Relations in the Development of Nervous System
By: Lijing Jiang
| Published: Nov 19, 2010
An important question throughout the history of embryology is whether the formation of a biological structure is predetermined or shaped by its…
Hamburger, Viktor, 1900-2001ExperimentsNervous SystemCell Death
"On the Nature of the Process of Fertilization and the Artificial Production of Normal Larvae (Plutei) From the Unfertilized Eggs of the Sea Urchin" (1899), by Jacques Loeb
By: Steve Elliott
| Published: Jun 10, 2010
Jacques Loeb developed procedures to make embryos from unfertilized sea urchin eggs in 1899. Loeb called the procedures "artificial parthenogenesis…
ParthenogenesisExperimentsSea Urchins
"β-Catenin Defines Head Versus Tail Identity During Planarian Regeneration and Homeostasis" (2007), by Kyle A. Gurley, Jochen C. Rink, and Alejandro Sánchez Alvarado
By: Mary E. Sunderland
| Published: Mar 15, 2010
Alejandro Sánchez Alvarado's laboratory group has employed molecular tools to investigate old questions about regeneration and as a result have…
RegenerationExperiments