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William Thomas Astbury studied the structures of fibrous materials, including fabrics, proteins, and deoxyribonucleic acid, or DNA, in England during…
DNAX-Ray CrystallographyX-ray crystallography--TechniqueNucleic AcidsDNA-protein interactionsDavid Baltimore studied viruses and the immune system in the US during the twentieth century. In 1975, Baltimore was awarded the Nobel Prize in…
Baltimore, DavidDNAAcquired Immunodeficiency SyndromeIn 2015, Junjiu Huang and his colleagues reported their attempt to enable CRISPR/cas 9-mediated gene editing in nonviable human zygotes for the first…
LiteratureDoudna, Jennifer A.Charpentier, Emmanuelle, 1968-Clustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsIn 2007, Dennis Lo and his colleagues used digital polymerase chain reaction or PCR to detect trisomy 21 in maternal blood, validating the method as…
Polymerase chain reactionNucleic Acid Amplification TechniquesDown syndromeDNAAneuploidyMary-Claire King studied genetics in the US in the twenty-first century. King identified two genes associated with the occurrence of breast cancer,…
GeneticsBreast--Cancer--SusceptibilityBreast--Cancer--Prognosis--Statistical methods--CongressesBreast--Cancer--ResearchDNA fingerprintingIn 2001, Yale University Press published Frederic Lawrence Holmes' book, Meselson, Stahl, and the Replication of DNA: A History of "The Most…
LiteratureWatson, James D., 1928-Crick, Francis, 1916-2004Marine Biological Laboratory (Woods Hole, Mass.)DNA ReplicationFranklin William Stahl studied DNA replication, bacteriophages, and genetic recombination in the US during the mid-twentieth and early twenty-first…
DNA SequenceNucleotide sequenceDNA ReplicationDNA--SynthesisDNA replication--RegulationSince the 1950s, scientists have developed interspecies blastocysts in laboratory settings, but not until the 1990s did proposals emerge to engineer…
BlastocystDiseasesbioethicsTadpoleCell nuclei--TransplantationCornelia Isabella Bargmann studied the relationship between genes, neural circuits, and behavior in the roundworm Caenorhabditis elegans (C. elegans…
Drosophila melanogasterNeural circuitryNeurobiologyHER-2 geneHER-2 proteinAlec John Jeffreys created a process called DNA fingerprinting in the UK during the twentieth century. For DNA fingerprinting, technicians identify a…
DNA fingerprintingForensic sciencesForensic AnthropologyMicrosatellites (Genetics)Exons (Genetics)