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The Notch Signaling Pathway in Embryogenesis
By: Justin Wolter
| Published: Mar 06, 2013
The Notch signaling pathway is a mechanism in animals by which adjacent cells communicate with each other, conveying spatial information and genetic…
EmbryologyDevelopmental BiologyEmbryosCell differentiationNotch genes
Epithelium
By: Kate MacCord
| Published: Oct 17, 2012
Frederik Ruysch, working in the Netherlands, introduced the term epithelia in the third volume of his Thesaurus Anatomicus in 1703. Ruysch created…
EpitheliumRuysch, Frederik, 1638-1731AnatomyCells--MorphologyHis, Wilhelm, 1831-1904
Gastrulation in Mus musculus (common house mouse)
By: Justin M. Wolter
| Published: Oct 04, 2012
As mice embryos develop, they undergo a stage of development called gastrulation. The hallmark of vertebrate gastrulation is the reorganization of…
GastrulationMiceGerm CellsSomatic embryogenesisEmbryos
Mesenchyme
By: Kate MacCord
| Published: Sep 14, 2012
Mesenchyme is a type of animal tissue comprised of loose cells embedded in a mesh of proteins and fluid, called the extracellular matrix. The loose,…
MesenchymeGastrulationStem CellsMesenchymal Stem CellsEmbryology
The Source-Sink Model
By: Jack Resnik
| Published: May 07, 2012
The source-sink model, first proposed by biologist Francis Crick in 1970, is a theoretical system for how morphogens distribute themselves across…
Crick, Francis, 1916-2004Nobel Prize winnersEmbryosMorphogenesisGenes
Spemann-Mangold Organizer
By: Samuel Philbrick, Erica O'Neil
| Published: Jan 12, 2012
The Spemann-Mangold organizer, also known as the Spemann organizer, is a cluster of cells in the developing embryo of an amphibian that induces…
EmbryosAmphibiansSpemann, Hans, 1869-1941EmbryologyGastrulation
Epigenetic Landscape
By: Adam R. Navis
| Published: Oct 30, 2007
The epigenetic landscape is a concept representing embryonic development. It was proposed by Conrad Hal Waddington to illustrate the various…
Waddington, C. H. (Conrad Hal), 1905-1975EpigeneticsCell differentiationEmbryologyDevelopmental Biology
"Proliferation, Differentiation and Degeneration in the Spinal Ganglia of the Chick Embryo under Normal and Experimental Conditions" (1949), by Viktor Hamburger and Rita Levi-Montalcini
By: Adam R. Navis
| Published: Oct 30, 2007
In this paper Viktor Hamburger and Rita Levi-Montalcini collaborated to examine the effects of limb transplantation and explantation on neural…
Chickens--EmbryosDevelopmental BiologyCell differentiationEmbryosLevi-Montalcini, Rita
"Experiments on Embryonic Induction III. A Note on Inductions by Chick Primitive Streak Transplanted to the Rabbit Embryo" (1934), by Conrad Hal Waddington
By: Adam R. Navis
| Published: Oct 30, 2007
Conrad Hal Waddington's "Experiments on Embryonic Induction III," published in 1934 in the Journal of Experimental Biology, describes the discovery…
Waddington, C. H. (Conrad Hal), 1905-1975EmbryosCell differentiationEmbryologyChickens--Embryos
Chemical Induction
By: Adam R. Navis
| Published: Oct 30, 2007
Research in chemical induction seeks to identify the compound or compounds responsible for differentiation in a developing embryo. Soren Lovtrup…
Cell differentiationEmbryosDevelopmental BiologyNotochordWaddington, C. H. (Conrad Hal), 1905-1975