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The Roslin Institute (1993- )
By: Zane Bartlett
| Published: Sep 29, 2014
The Roslin Institute was established in 1993 in the village of Roslin, Scotland, as an independent research center by the Biotechnology and…
OrganizationCloningGenetic EngineeringHuman CloningOrganizations
"Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts" (1997), by Angelika E. Schnieke, et al.
By: Zane Bartlett
| Published: Aug 19, 2014
In the 1990s, researchers working at the Roslin Institute in Edinburgh, Scotland, performed cloning experiments in collaboration with PPL…
CloningChristmas FactorBlood coagulation factor IXRoslin InstituteWilmut, Ian
Apoptosis in Embryonic Development
By: Zane Bartlett
| Published: Jun 08, 2017
Apoptosis, or programmed cell death, is a mechanism in embryonic development that occurs naturally in organisms. Apoptosis is a different process…
ApoptosisGenetic regulationCaenorhabditis elegansCellsGerm Cells
Paternal Sperm Telomere Elongation and Its Impact on Offspring Fitness
By: Joanna Yang, Zane Bartlett
| Published: Feb 07, 2017
Telomeres are structures at the ends of DNA strands that get longer in the DNA of sperm cells as males age. That phenomenon is different for most…
TelomereAgingSpermSpermatozoaTelomerase
Somatic Cell Nuclear Transfer in Mammals (1938-2013)
By: Zane Bartlett
| Published: Nov 04, 2014
In the second half of the twentieth century, scientists learned how to clone organisms in some species of mammals. Scientists have applied somatic…
CloningCell nuclei--TransplantationSpemann, Hans, 1869-1941Genetic Engineering
Telomerase in Human Development
By: Zane Bartlett
| Published: Mar 23, 2015
Telomerase is an enzyme that regulates the lengths of telomeres in the cells of many organisms, and in humans it begins to function int the early…
TelomeraseTelomereDNAMolecular BiologySomatic embryogenesis
"Viable Offspring Derived from Fetal and Adult Mammalian Cells" (1997), by Ian Wilmut et al.
By: Zane Bartlett
| Published: Oct 10, 2014
In the 1990s, Ian Wilmut, Jim McWhir, and Keith Campbell performed experiments while working at the Roslin Institute in Roslin, Scotland. Wilmut,…
CloningMolecular CloningClone CellsCampbell, Keith, 1954-2012Roslin Institute
Telomeres and Telomerase in Cellular Aging (Senescence)
By: Zane Bartlett
| Published: Feb 11, 2015
Telomeres are sequences of DNA on the ends of chromosomes that protect chromosomes from sticking to each other or tangling, which could cause…
TelomeraseGreider, Carol W.Wistar Institute of Anatomy and BiologyAgingDNA
Keith Henry Stockman Campbell (1954-2012)
By: Zane Bartlett
| Published: Jun 27, 2014
Keith Henry Stockman Campbell studied embryo growth and cell differentiation during the twentieth and twenty-first centuries in the UK. In 1995,…
Campbell, Keith, 1954-2012Wilmut, IanCloningStem CellsFibroblasts
Elizabeth Blackburn, Carol Greider and Jack Szostak's Telomere and Telomerase Experiments (1982-1989)
By: Zane Bartlett
| Published: Mar 24, 2015
Experiments conducted by Elizabeth Blackburn, Carol Greider, and Jack Szostak from 1982 to 1989 provided theories of how the ends of chromosomes,…
TelomereGreider, Carol W.Chromosome replicationTelomeraseDNA