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The p53 protein acts as a pivotal suppressor of inappropriate cell proliferation. By initiating suppressive effects through induction of apoptosis,…
Tumor Suppressor Protein p53ExperimentsCancerCell Death"Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics" (hereafter abbreviated as "Apoptosis") was published in…
LiteratureApoptosisPublicationsCancerCell DeathThe review article “Cell Deaths in Normal Vertebrate Ontogeny” (abbreviated as “Cell Deaths”) was published in Biological Reviews of the Cambridge…
LiteratureCell DeathPublicationsVertebratesOntogenyGerman embryologist Viktor Hamburger came to the US in 1932 with a fellowship provided by the Rockefeller Foundation. Hamburger started his research…
LiteraturePublicationsExperimentsNervous SystemChicksAn important question throughout the history of embryology is whether the formation of a biological structure is predetermined or shaped by its…
Hamburger, Viktor, 1900-2001ExperimentsNervous SystemCell DeathIn the 1910s, Alexis Carrel, a French surgeon and biologist, concluded that cells are intrinsically immortal. His claim was based on chick-heart…
ContextCarrel, Alexis, 1873-1944Tissue Culture TechniquesTissue cultureChicksAdvanced Cell Technology, Inc. (ACT) is a biotechnology company that uses stem cell technology to develop novel therapies in the field of…
OrganizationStem CellsOrganizationsReproductionRegenerationMichael D. West is a biomedical entrepreneur and investigator whose aim has been to extend human longevity with biomedical interventions. His focus…
PeopleStem CellsBiographyRegenerationAlexis Carrel, the prominent French surgeon, biologist, and 1912 Nobel Prize laureate for Physiology or Medicine, was one of the pioneers in…
TechnologyCarrel, Alexis, 1873-1944Tissue Culture TechniquesTissue culture