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Thesis: A History of Cellular Senescence and Its Relation to Stem Cells in the Twentieth and Twenty-First Centuries
By: Zane Bartlett
| Published: Dec 16, 2020
This study aims to provide information to answer the following question: While some scientists claim they can indefinitely culture a stem cell line…
AgingsenescenceCell Culture TechniquesCell culturePublications
The Effects of Gene Regulation on Aging in Caenorhabditis elegans (2003)
By: Dasia Garcia
| Published: Feb 16, 2017
In 2003, molecular biology and genetics researchers Coleen T. Murphy, Steven A. McCarroll, Cornelia I. Bargmann, Andrew Fraser, Ravi S. Kamath, Julie…
Caenorhabditis elegansCaenorhabditisInsulin-like growth factor-binding proteinsIGF-Binding ProteinsGenetic regulation
Paternal Sperm Telomere Elongation and Its Impact on Offspring Fitness
By: Joanna Yang, Zane Bartlett
| Published: Feb 07, 2017
Telomeres are structures at the ends of DNA strands that get longer in the DNA of sperm cells as males age. That phenomenon is different for most…
TelomereAgingSpermSpermatozoaTelomerase
Telomeres and Telomerase in Cellular Aging (Senescence)
By: Zane Bartlett
| Published: Feb 11, 2015
Telomeres are sequences of DNA on the ends of chromosomes that protect chromosomes from sticking to each other or tangling, which could cause…
TelomeraseGreider, Carol W.Wistar Institute of Anatomy and BiologyAgingDNA
The Hayflick Limit
By: Zane Bartlett
| Published: Nov 14, 2014
The Hayflick Limit is a concept that helps to explain the mechanisms behind cellular aging. The concept states that a normal human cell can only…
CellsCell populationsCell DeathApoptosisCell Proliferation
Leonard Hayflick (1928- )
By: Zane Bartlett
| Published: Jul 20, 2014
Leonard Hayflick studied the processes by which cells age during the twentieth and twenty-first centuries in the United States. In 1961 at the Wistar…
PeopleCellsCell populationsCell DeathApoptosis